Specificity of association in epidemiology

نویسندگان

چکیده

Abstract The epidemiologist Bradford Hill famously argued that in epidemiology, specificity of association (roughly, the fact an environmental or behavioral risk factor is associated with just one at most a few medical outcomes) strong evidence causation. Prominent epidemiologists have dismissed Hill’s claim on ground it relies dubious `one-cause effect’ model disease paper examines this methodological controversy, and argues considerations do useful role to play causal inference epidemiology. More precisely, I argue help solve pervasive inferential problem contemporary epidemiology: determining whether exposure-outcome correlation might be due confounding by social factor. This examination has interesting consequences for our understanding methodology It highlights how epidemiology local tools designed address specific problems peculiar discipline, shows observational can proceed little prior knowledge structure phenomenon investigated. also cannot (despite claims contrary) entirely explained terms Woodward’s well-known concept “one-to-one” specificity. because as understood depends exposure (or outcome) `heterogeneous’ set variables. dimension heterogeneity not captured notion, but crucial evidential import association.

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ژورنال

عنوان ژورنال: Synthese

سال: 2022

ISSN: ['0039-7857', '1573-0964']

DOI: https://doi.org/10.1007/s11229-022-03944-z